Parkinson’s is a dangerous and developing disease. In this disease, some neurons in the brain stem become inactive. In today’s research, researchers have found that the activation of these neurons can cure the symptoms of Parkinson’s disease in mice. Using this research, neuroscientists are looking for a treatment for Parkinson’s for all people worldwide. Today, doctors are continuously trying to treat this disease, and we also hope they can improve the treatment of movement symptoms in Parkinson’s disease. In the rest of this article, we will thoroughly review the neuroscience network of Parkinson’s disease and discuss the efforts of researchers and the discovery of its treatment.

What kind of disease is Parkinson’s?

In Parkinson’s disease, cells in the part of the brain that secrete the neurotransmitter dopamine are destroyed. Parkinson’s is a neurodegenerative disease that gradually causes the dopaminergic neurons to disappear in the brain stem. With the destruction of a neuron, the body’s muscles become stiff, and body movements slow down. Tremors of the hands and feet in the normal state and at rest can occur in patients with Parkinson’s disease. Difficulty in walking and moving is another symptom of Parkinson’s disease.

The symptoms of Parkinson’s disease can vary from person to person. The severity of the symptoms of this disease varies from person to person. Most people suffering from this disease cannot generally move because their bodies are locked while walking, and they stay home. But for Treatment for Parkinson’s, doctors prescribe drugs that improve body movements.

Treatment of Parkinson’s disease

To treat Parkinson’s, doctors first prescribe a drug that turns into the neurotransmitter dopamine in the brain. But the existing drugs cannot treat many of the symptoms of this disease. So neuroscience researchers use deep brain stimulation (DBS) and medication to treat Parkinson’s. The surgeon uses a thin metal wire in DBS to send electrical pulses. A metal wire is surgically placed in the brain of patients, and this causes the symptoms of Parkinson’s disease to be treated. This process is effective for symptoms such as tremors, but more complex problems such as gait and body locking remain.

Treatment of factors that prevent walking is still a problem; many people suffer from this problem. Today, studies from the University of Copenhagen have investigated BDS in laboratory organisms such as mice. They believe that by placing particular neurons in the brain stem, they can treat consequences such as walking with Parkinson’s disease. This is fantastic news that can heal so many people.

Brain stem DBS as a method for treatment for Parkinson’s

In recent years, many researchers have conducted studies to find a treatment for Parkinson’s, including improving walking symptoms. Based on these studies and research, scientists hypothesize that freezing in walking can be improved by using BDS. This requires BDS to stimulate neurons in the nucleopontine nucleus of the PPN. Based on the research and studies of scientists in this field, PPN sends signals from the brain to the spinal cord that cause body movements and improve freezing.

After researching and studying this hypothesis, neuroscientists experimented on animals. These experiments show that stimulation of PPN excitatory neurons can induce locomotion in normal mice. After performing this test, the possibility of this process affecting Treatment for Parkinson’s increased.

Experiments conducted on animals for the treatment of Parkinson’s

As mentioned, it is not possible to treat some movement symptoms of Parkinson’s with drugs. Therefore, neuroscientists studied deep brain stimulation to treat this disease. Experimenting with animals found the effect on body movements when they stimulated neurons in the caudal part of the PPN. Based on this experiment, the animals could move naturally over long distances without any problems. Movement and walking occurred while showing signs of Parkinson’s disease before the stimulation.

Neuroscience researchers compared the results obtained by stimulating different animal brain cells. Interestingly, all these experiments showed the same effect. This research suggests that excitatory neurons in the caudal PPN could be a way to treat Parkinson’s. All research and discovery of cures or diseases have been through experiments on mice. So successful treatment trials for Parkinson’s on animals can be a way to achieve great results.

Conclusion of Treatment for Parkinson’s

In this article from Neuroscience Network about Treatment for Parkinson’s, we examined a new treatment method for Parkinson’s. We said that some symptoms of Parkinson’s, such as body movements and walking, do not help the patient much by prescribing medication. As a result, scientists and researchers started studying BDS to treat Parkinson’s to improve this disease. After studying this topic, researchers looked at experiments on animals such as mice. These experiments suggest that stimulating neurons in the caudal PPN could be a way to treat Parkinson’s disease.